The Relationship Between Cervical Cancer Knowledge Levels and Interest in HPV Vaccination Among Female Patients at the Obgyn Clinic of RSU Haji Medan

Authors

  • M. Hafiz Iqreza Universitas Muhammadiyah Sumatera Utara
  • Dona Wirniaty Universitas Muhammadiyah Sumatera Utara

Keywords:

Cervical cancer, HPV, Gynecologic cancer, Level of knowledge

Abstract

Background: Cervical cancer ranks as the highest gynecological malignancy globally. Anatomically, this condition is a malignant process occurring in the cervix or uterine neck, a cylindrical area in the lower third of the uterus that protrudes and connects to the vagina via the external os. Objective: This study aims to analyze the relationship between the level of knowledge regarding cervical cancer and the interest in receiving HPV vaccination among female patients at the Obgyn Clinic of RSU Haji Medan. Methods: This research employed a non-experimental analytical observational design with a cross-sectional approach, where data collection was conducted purely through observation without intervention on 25 study subjects. Results: Among the total respondents, the group with good knowledge and high interest in vaccination comprised 11 individuals (44%), whereas 2 individuals (8%) showed no interest. In the group with sufficient knowledge, 3 individuals (12%) were interested and 2 individuals (8%) were not interested. Meanwhile, in the group with poor knowledge, only 1 individual (4%) expressed interest, while the remaining 6 individuals (24%) had no interest in vaccination. Conclusion: Evaluation using the Mann-Whitney test yielded a p-value of 0.003 (p-value less than 0.05). This proves a statistically significant relationship between the level of knowledge about cervical cancer and female patients' interest in undergoing HPV vaccination

References

D. Legianawati, I. M. Puspitasari, A. A. Suwantika, and A. Kusumadjati, “Profil Penatalaksanaan Kanker Serviks Stadium IIB–IIIB dengan Terapi Radiasi dan Kemoradiasi di Rumah Sakit Umum Pusat Dr. Hasan Sadikin Bandung Periode Tahun 2015–2017,” Indonesian Journal of Clinical Pharmacy, vol. 8, no. 3, 2019, doi: 10.15416/ijcp.2019.8.3.205.

S. Zhang, H. Xu, L. Zhang, and Y. Qiao, “Cervical cancer: Epidemiology, risk factors and screening,” Chinese Journal of Cancer Research, vol. 32, no. 6, pp. 720–728, 2020, doi: 10.21147/j.issn.1000-9604.2020.06.05.

A. M. Sutjipto and J. M. Pinariya, “Pengenalan Vaksinasi HPV oleh Koalisi Indonesia Cegah Kanker Serviks dengan Pendekatan Teori Difusi Inovasi,” vol. 5, no. 4, 2018.

E. Setianingsih, Y. Astuti, and N. Aisyaroh, “Literature Review: Faktor-Faktor yang Mempengaruhi Terjadinya Kanker Serviks,” vol. 7, no. 5, 2019.

S. D. Purba, “Hubungan Tingkat Pengetahuan Kanker Serviks dengan Minat untuk Vaksinasi HPV pada Mahasiswi Fakultas Kedokteran Universitas HKBP Nommensen Medan,” NJM, vol. 6, no. 2, 2021.

I. G. H. E. Adnyana, A. N. Toemon, and I. W. B. Satyaguna et al., “Hubungan Tingkat Pengetahuan Kanker Serviks dengan Minat Vaksinasi HPV pada Mahasiswi Fakultas Ekonomi Universitas Palangka Raya,” vol. 6, no. 2, 2023.

E. A. Cahyono et al., “Pengetahuan,” vol. 8, no. 2, 2019.

D. Mitra and R. Husada, “Hubungan Pengetahuan dengan Vaksinasi Virus (HPV) pada Wanita Usia Subur,” vol. 2, no. 3, 2018.

C. P. Yekti et al., “Faktor-Faktor Pendorong Minat,” Jurnal Riset Ekonomi dan Bisnis, vol. 4, no. 3, pp. 207–221, 2021.

A. S. Rahayu, “Infeksi Human Papilloma Virus (HPV) dan Pencegahannya pada Remaja dan Dewasa Muda,” vol. 7, no. 3, 2019.

D. Ayumaruti and D. Anshari, “Pengetahuan, Persepsi, Motivasi Masyarakat Tentang Vaksinasi HPV bagi Remaja Putri dan Wanita Usia Subur: Literature Review,” MPPKI, vol. 6, no. 4, 2023.

R. Norazizah, N. Khofiyah, and D. A. Rochmaniah, “Hubungan Paritas dan Jenis Kontrasepsi dengan Kejadian Lesi Pra-kanker Serviks di Yayasan Kanker Kalimantan Selatan,” Jurnal Berkala Kesehatan, vol. 5, no. 1, p. 35, 2019, doi: 10.20527/jbk.v5i1.6362.

S. Clara, “Predisposisi dan Upaya Prevensi Keganasan Kanker Serviks pada Wanita,” Proceeding of Sari Mulia University Midwifery National Seminars, vol. 5, no. 8, 2019.

D. M. Fitri and E. Elviany, “Hubungan Pengetahuan, Persepsi, dan Sikap dengan Minat untuk Melakukan Vaksinasi Human Papilloma Virus (HPV) pada Wanita Usia Subur di Desa Gudang Kecamatan Cikalongkulon Kabupaten Cianjur Tahun 2018,” Jurnal Kesehatan dan Kebidanan, vol. 7, 2018.

P. R. Evriarti and A. Yasmon, “Patogenesis Human Papillomavirus (HPV) pada Kanker Serviks,” vol. 7, no. 1, 2020.

V. M. Williams, M. Filippova, U. Soto, and P. J. Duerksen-Hughes, “HPV-DNA integration and carcinogenesis: Putative roles for inflammation and oxidative stress,” Future Virology, vol. 6, no. 1, pp. 45–57, 2011, doi: 10.2217/fvl.10.73.

M. Wahidin and R. Febrianti, “Gambaran Pelaksanaan Program Vaksinasi Human Papillomavirus (HPV) di Dua Puskesmas di Kota Jakarta Pusat Tahun 2022,” pp. 182–191, 2021.

M. A. Jones and R. L. Cook, “Intent to receive an HPV vaccine among university men and women and implications for vaccine administration,” Journal of American College Health, vol. 57, no. 1, pp. 23–32, 2008, doi: 10.3200/JACH.57.1.23-32.

M. Arevalo et al., “Factors related to human papillomavirus vaccine uptake and intentions among adults aged 18–26 and 27–45 years in the United States: A cross-sectional study,” Cancer, vol. 129, no. 8, pp. 1237–1252, 2023, doi: 10.1002/cncr.34680.

F. R. Anggraini, “Tingkat Pengetahuan Kanker Serviks dan Pengetahuan Cara Pencegahan Kanker Serviks di Fakultas Bisnis Universitas Katolik Widya Mandala Surabaya,” Skripsi, Program Studi Pendidikan Dokter, Universitas Katolik Widya Mandala Surabaya, Surabaya, 2014.

E. M. Moegni, “Penilaian Pengetahuan, Sikap, dan Perilaku Pasien Poliklinik Kebidanan dan Kandungan RSUPN Dr. Cipto Mangunkusumo Tentang Pap Smear,” Indonesian Journal of Obstetrics and Gynecology, 2016.

E. Yuliaswati and Kamidah, “Peningkatan Pengetahuan Tentang IVA Tes untuk Deteksi Dini Kanker Leher Rahim,” GEMASSIKA: Jurnal Pengabdian Kepada Masyarakat, vol. 3, no. 2, pp. 125–133, 2019, doi: 10.30787/gemassika.v3i2.518.

N. Runiari, D. A. K. Surinati, and C. D. Utami, “Motivasi Remaja Putri dalam Melaksanakan Vaksinasi Human Papilloma Virus (HPV),” Jurnal Gema Keperawatan, vol. 8, no. 2, pp. 169–174, 2015.

A. Herawati, L. Kusumawati, and A. Hidayat, “Hubungan Pengetahuan dan Motivasi Karyawan Rumah Sakit Sari Mulia untuk Melakukan Vaksinasi HPV,” Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan, vol. 9, no. 1, pp. 502–510, 2018.

S. Pratamaningtyas, “Hubungan Antara Pengetahuan Wanita Usia 15–26 Tahun dengan Minat Mengikuti Imunisasi HPV (Studi di Desa Wonorejo Kecamatan Ngadiluwih Kabupaten Kediri),” Jurnal Penelitian Kesehatan Suara Forikes, vol. 4, no. 1, pp. 1–5, 2013.

Published

2026-09-24

How to Cite

Iqreza, M. H., & Wirniaty, D. (2026). The Relationship Between Cervical Cancer Knowledge Levels and Interest in HPV Vaccination Among Female Patients at the Obgyn Clinic of RSU Haji Medan. Jurnal Kesehatan Republik Indonesia, 3(10), 163–168. Retrieved from https://jurnal.intekom.id/index.php/jkri/article/view/2408